Monitoring Fluid-Bed Granulation and Milling Processes In-Line with Real-Time Imaging
نویسندگان
چکیده
Granulation methods are used in the pharmaceutical sector to enlarge and densify small powder particles into larger ones, typically to improve powder flow so that the material can be processed effectively and efficiently into solid dosage forms. In addition, granulation methods are important for “locking in” the API within the formulation, thereby reducing the risk of segregation. Granulated material is attained by direct size enlargement of primary particles or size reduction from dry compacted material (1).
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